A 6-year-old boy died and 11 others were hurt when their church bus overturned near Indianapolis in an accident that police said appeared to be the result of an error by a driver with a suspended license.

As the leader of a hospital in one of Chicago's most impoverished neighborhoods, Edward Novak often championed himself as a down-to-earth businessman who brought access to health care to those otherwise ignored.

Two men arrested for illegally hunting a protected lion are in court on Wednesday in Zimbabwe to face poaching charges.

Hours after reportedly calling on U.S. Sen. Mark Kirk to halt his re-election bid, a major Republican fundraiser backtracked Tuesday and hailed Kirk as the party's best candidate for one of the nation's most hotly contested Senate seats.

A 7-month-old boy was listed in "very critical" condition after being left in a car for two hours in a Joliet parking lot.

An Afghan official said Wednesday his government is examining claims that reclusive Taliban leader Mullah Mohammed Omar is dead. The Taliban could not be immediately reached on the government's comments about Omar, who has been declared dead many t...

A bicyclist was killed and a motorcyclist was injured in a crash in Old Irving Park early Wednesday, police said.

A man has died after being pulled from the water near Oak Street Beach early Wednesday, police said.

A man was killed and at least seven people have been wounded in city shootings since Tuesday afternoon, police said.

Chicago police Officer Lynn Casey thought she heard fireworks exploding outside the front door of an Englewood police deployment center where she was working desk duty.